Circulating Platelet-Neutrophil Aggregates Play a Significant Role in Kawasaki Disease

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چکیده

منابع مشابه

Circulating platelet-neutrophil aggregates play a significant role in Kawasaki disease.

BACKGROUND Circulating platelet-neutrophil aggregates play a crucial role in amplifying acute inflammation and could promote adverse effects involving vascular injury. The aim of this study was to evaluate the role of platelet-neutrophil aggregates in Kawasaki disease (KD). METHODS AND RESULTS Forty patients with KD (30 intravenous immunoglobulin [IVIG] responders and 10 IVIG non-responders),...

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Do patients with thromboembolic disease have circulating platelet aggregates?

Reports of circulating platelet aggregates (ie, microemboli) in thromboembolism and other vascular disorders are based on a method (Wu and Hoak , 1974) in which venous blood is collected via scalp vein needle and tubing into either formaldehyde, which fixes aggregates, or EDTA, which disperses them. The ratio of platelet counts in platelet-rich plasma (PRP) from the two blood samples after cent...

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Behçet’s Disease: Do Natural Killer Cells Play a Significant Role?

Behçet's disease (BD) is a complex inflammatory disease, of unknown etiology. While disease pathogenesis remains unclear, a strong relationship between BD and HLA-B*51 has been established over the last 30 years. A number of theories exist regarding the cause of BD; however, few are able to account for the increased rates of HLA-B*51 positive individuals, particularly around the Mediterranean b...

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Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease.

OBJECTIVES We sought to examine whether patients with stable coronary artery disease (CAD) have increased platelet reactivity and an enhanced propensity to form monocyte-platelet aggregates. BACKGROUND Platelet-dependent thrombosis and leukocyte infiltration into the vessel wall are characteristic cellular events seen in atherosclerosis. METHODS Anticoagulated peripheral venous blood from 1...

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Kawasaki Disease in Children: A Case Report.

SUMMARY: Kawasaki is an acute multisystemic disease affecting Predominantly. Children below 4 years of age. Having a Self- limited Course, it often Presents as Vasculitis. The Principal Complications are Stomatitis, conjunctivitis. Lymphadenopathy, Skin rashes as well as involvment of cardiovascular, alimentary and nervous system. In this article we report the First case of Kawasaki Disease ...

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ژورنال

عنوان ژورنال: Circulation Journal

سال: 2015

ISSN: 1346-9843,1347-4820

DOI: 10.1253/circj.cj-14-1323